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The divergent immunomodulatory effects of short chain fatty acids and medium chain fatty acids

GLP-1 receptor agonists such as semaglutide and the dual GIP/GLP-1 agonist tirzepatide act on appetite, satiety, and gastric emptying, with evidence from programs like STEP (NEJM, 2021), SURMOUNT (NEJM, 2022), and SURMOUNT-OSA (NEJM, 2024)